منابع مشابه
Ancestral Reconstruction
Ancestral reconstruction is the extrapolation back in time from measured characteristics of individuals (or populations) to their common ancestors. It is an important application of phylogenetics, the reconstruction and study of the evolutionary relationships among individuals, populations, or species to their ancestors. In the context of biology, ancestral reconstruction can be used to recover...
متن کاملAncestral sequence reconstruction with phangorn
For parsimony analysis of the edge length represent the observed number of changes. Reconstructiong ancestral states therefore defines also the edge lengths of a tree. However there can exist several equally parsimonious reconstructions or states can be ambiguous and therefore edge length can differ. ”MPR” reconstructs the ancestral states for each (internal) node as if the tree would be rooted...
متن کاملReconstruction of Ancestral Protosplice Sites
Most of the eukaryotic protein-coding genes are interrupted by multiple introns. A substantial fraction of introns occupy the same position in orthologous genes from distant eukaryotes, such as plants and animals, and consequently are inferred to have been inherited from the common ancestor of these organisms. In contrast to these conserved introns, many other introns appear to have been gained...
متن کاملAncestral Reconstruction for Association Mapping
One of the greatest promises of modern genetics is the ability to identify loci responsible for, or at least highly correlated with, important physical traits and disease susceptibility. This will enable benefits ranging from improved disease risk assessment and crop design to ultimately a better understanding of how genotype variation effects variations in phenotypes. A key component in this t...
متن کاملAncestral Genome Reconstruction in Bacteria
The rapid accumulation of numerous sequenced genomes has provided a golden opportunity for ancestral state reconstruction studies, especially in the whole genome reconstruction area. However, most ancestral genome reconstruction methods developed so far only focus on gene or replicon sequences instead of whole genomes. They rely largely on either detailed modeling of evolutionary events or edit...
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ژورنال
عنوان ژورنال: PLOS Computational Biology
سال: 2016
ISSN: 1553-7358
DOI: 10.1371/journal.pcbi.1004763